The Administration Effectiveness Of The Extract Of Sunti Aceh (Dried Averrhoa Bilimbi L.) Towards Reduction In Blood Sugar Levels In Diabetic Rats

Abstract

Introduction: West Aceh has diabetes prevalence above the national prevalence rate, namely >30,8%. One of the causative factors of the high number in diabetes cases is dietary, such as the habit of not consuming healthy food, so it is important to have healthy foods in the form of herbal medicines that are able to control blood sugar levels in diabetics. This study aims to measure the effectiveness of administrating the extract of dried Averrhoa bilimbi L. (sunti aceh) to reduce blood sugar levels in diabetic rats. Material and Method This is an experimental study with the research plan of pre and post test of randomized controlled group design, the experimental animals were 15 rats which were divided into 3 groups, namely group 1 distilled water (negative control), group 2 metformin at a dose of 500mg/BWgr (positive control), group 3 the extract of sunti aceh (ESA) at a dose of 750mg/BWgr. All groups were first induced with alloxan until their blood sugar levels reached 200mg/dl.  After four weeks of treatment, blood sugar levels were measured, then a decrease in blood sugar levels was observed. Results The study showed that group 1 did not experience a significant decrease in blood sugar levels between pre and post test at p>0.05, while groups 2 and 3 experienced a significant decrease in blood sugar levels between pre and posttest at p <0.05. Groups 2 and 3 both have a better level of effectiveness than distilled water. Conclusion Groups 2 and 3 have the same level of effectiveness in reducing blood sugar levels.