Celiac Disease Prevalence In Patients With Type 1 Diabetes From Saudi Arabia

Abstract

Celiac disease (CD) has a recognized association with type 1 diabetes. T1DM is an AD in which insulin deficiency results from the destruction of pancreatic beta cells caused by the autoantibodies. Aims: The research aims to study the prevalence of celiac disease in patients with type 1 diabetes, and to study digestive symptoms in patients with diabetes in general, because the early diagnosis of celiac disease, which is attached, prevents complications for both diseases and helps in controlling blood sugar. Subjects and Methods: A descriptive research design was utilized to gather information about screening practices for celiac disease in patients with type 1 diabetes. This present study was carried out in the Clinics of Pediatric Gastroenterology and Endocrinology. 92 patients with type 1 DM were included in the study. Results: Findings indicate that prevalence of CD was about 11.95%(11/92) in Saudi Arabia .There is no gender differences (between males and females). The difference between the two groups in Diabetes duration was significant. Diabetes duration for  Celiac disease positivity   group  was 12.42. , while for Celiac disease negativity  group was 15.02(p-value smaller than .05 ).Flatulence, loose stools and diarrhea  ere the most common clinical symptom in patients with type 1 diabetes, regardless of antibody positivity or negativity. There is a significant difference between the two groups in Hb(p-value smaller than .05 ) and  Ca(p-value smaller than .05 ). Conclusion: This study confirms that the celiac disease is common in type 1 patients with diabetes.