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In the study, rehabilitation treatments were performed in patients with rheumatoid arthritis (RA) and ankylosing spondylitis (AS) with renal injury. The aim of the study was to evaluate the effectiveness of rehabilitation methods in improving its performance in patients with rheumatoid arthritis and ankylosing spondylitis with chronic kidney disease. A total of 125 patients were examined during the study, including 84 patients with rheumatoid arthritis and 41 patients with ankylosing spondylitis. Physical, mechanical and climatic factors of treatment in patients after main treatment therapy led to a significant improvement in the main clinical signs of RA and AS disease.