THE INCIDENCE OF CORONARY HEART DISEASE IN THE PRESENCE AND VARIOUS COMBINATIONS OF INDIVIDUAL COMPONENTS OF THE METABOLIC SYNDROME

Abstract

The aim was to study the significance of individual components of metabolic syndrome and their various combinations as risk factors for coronary heart disease.

Material and methods. The study included 1335 males representing a representative sample of the unorganized population of the city of Tashkent (Uzbekistan). Some risk factors of coronary heart disease (including the main components of metabolic syndrome) were studied. Mathematical processing was determinedcorrelation indicators, average and relative values of the studied risk factors.

Results. The differences in correlations between different risk factors of coronary heart disease were revealed. Coronary heart disease has been shown to be associated with all major components of metabolic syndrome. However, the severity of these relationships varies. As the number of risk factors in the structure of coronary heart disease increases, the proportion of typical angina pectoris decreases, and the proportion of pain-free and atypical manifestations of coronary heart disease increases. Among individuals with MS, the frequency of pain-free and atypical manifestations of coronary heart disease is 3.63 times higher than typical angina pectoris.

Summary. The connection between coronary heart disease and the main components of metabolic syndrome has been established. It is shown that with impaired glucose tolerance, pain-free and atypical variants of the course of this disease are more common.