Antifungal activity of Ficus benghalensis and Vachellia nilotica against denture plaque Candida albicans-an invitro study

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Krishanga Srivastava , Jacob Mathew Philip , Helen Mary Abraham , C. J.Venkatakrishnan

Abstract

Background-


Denture plaque Candida are opportunistic fungi that can cause various oral disease in certain conditions. The purpose of this study is to evaluate the antifungal effect of extracts of Ficus benghalensis and Vachellia nilotica against denture plaque Candida albicans to observe if their herbal extracts can potentially be used in the management of oral candidiasis.


Materials and Methods-


Antifungal activity was assessed using above mentioned plant extracts against strains of C. albicans isolated from 50 samples of denture plaque using 2 concentrations (5mg/ml and 10 mg/ml) in a liquid medium based anti-fungal assays.


Results-


The alcoholic and aqueous extracts of V.nilotica and the aqueous extract of F.benghalensis exhibited anti-candidal activity against 46 samples out of the 50 samples of C. albicans in both concentrations. Extracts prepared with other solvents did not demonstrate anti-candidal activity.


Conclusion-


The alcoholic and aqueous extracts of V.nilotica and F.benghalensis have demonstrated anticandidal property and can be incorporated into various denture hygiene products to prevent candida associated denture stomatitis.

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