“Association OF Type 2 Diabetes Mellitus, Depression, Anxiety AND Cognitive Impairment”

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Lalramengmawii , Anand Vijayakumar Palur Ramakrishnan


Association of diabetes with mental health is an emerging condition worldwide that worsens the symptoms as well as diabetes-associated complications. Early prevention & management of disease complications, medication adherence, awareness and regular screening of patients’ health is important. The aim and scope of this review is to highlight and provide an overview of the already existing research paper on diabetes and how it affects the brain by causing mental stress, disease complications, the importance of patient counseling, and to improve the disease progression, symptoms, and quality of life. Following PRISMA guidelines manuscripts published between the years 2008 to 2022 were searched in databases: PubMed, Web of Science & ScienceDirect. A total of 32 papers were identified and cross-sectional study, random sampling, longitudinal study, descriptive survey design, multinational randomized trial, case-control study, population-based inception cohort study, epidemiological enquiry study, non-interventional study and convenience sampling method were included. The study population included both men and women suffering from type 1 diabetes and type 2 diabetes and gestational diabetes mellitus (GDM). It is clear that patients with diabetes are associated with anxiety, depression & cognition and from the selected data, the rate of depression was 40.7%, the anxiety level was found to be 33.9% while cognitive function decline was mostly seen in the older age population 29.9%. Preventing the negative outcomes to delay the progression of disease and improve quality of life of a patient to give them hope, positive thoughts and improve overall diabetes management is important. Thus, providing patient counseling and suitable management of diabetes symptoms and mental health disease should be considered to attain psychological well-being and enhance medical outcomes.

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