Mechanism Of Action Of Covid 19 And Its Manifestations

Abstract

Various Neurological Manifestation associated with severe acute respiratory syndrome (SARS- CoV-2) has been recorded ranging from mild to severe symptoms and syndromes. An intense review of all the current published literature was conducted and found that headache, psychomotor agitation, taste and smell abnormalities, generalized muscle weakness, and Myalgia were the common neurological manifestation of SARS CoV-2. However, Seizures, stroke, flaccid paralysis, and Guillain-Barre syndrome were some of the rarely found cases among COVID 19 patients. the SARS CoV-2 virus has been found in over a hundred countries across the world. In March 2020, the World Health Organization declared a pandemic after receiving reports of more than 700,000 deaths worldwide (WHO). While first believed to be limited in its effects, the virus soon progressed to other organs, including the central nervous system (CNS), leading to symptoms such as paralysis and death. For a long time, it was thought that viral entrance into host cells through the receptor ACE2 was the key determinant of the S protein of CoV-2 linked to the SARS membrane.