An Overview Organophosphate Poisoning, Role Of Anesthesia, Pharmacist, Clinical Laboratory And Paramedics In The Management Approach

Abstract

Organophosphates are compounds that are frequently employed as pesticides. They function to block acetylcholinesterase, which results in an accumulation of acetylcholine at muscarinic and nicotinic receptors located all throughout the body. Although poisonings are typically thought of as low-volume, chronic cases that are caused by agricultural exposures, they can also manifest as attempts at suicide that are caused by the consumption of organophosphates. When organophosphate poisoning occurs, especially when substantial quantities are consumed, it is imperative that treatment be initiated as quickly and effectively as possible. Literature review give an example that demonstrates how to effectively manage severe organophosphate toxicity symptoms. In the management approach, the roles of anesthesia, chemist, clinical laboratory, and paramedics are extremely important. They work together as a collaborative team beginning with prehospital care and continuing through emergency department admissions and intensive care unit admissions.