Enhancing Accuracy and Efficiency of Complete Blood Count (CBC) and Biochemistry Analysis in Medical Laboratories

Abstract

Complete blood count (CBC) and biochemistry analysis in medical laboratories are routine tests for the diagnosis and monitoring of any disease. In a CBC test, if a sample of blood is mixed with the diluted solution, the elements that form behave in different ways. The red cells settle to the bottom of the solution, but the white cells and platelets are held in suspension. The white cells and platelets are not homogeneous in their distribution; the red cells can settle through the white cells to the bottom of the sample tube. And in biochemistry analysis, the high cost and lengthy time for the several tests for diagnosis were the main drawbacks. To overcome this problem, we are developing an automatic blood analyzer that has an accurate and efficient differential counter. This instrument will eliminate most of the manual procedures to reduce human error and provide an accurate count of different types of cells in the blood. For biochemistry analysis, we are using a Lab-on-Chip device. Since the CBC test and biochemistry analysis are the most commonly performed tests in medical laboratories, the new development of automatic analyzers and lab-on-chip devices will bring a great advantage in terms of rapid, accurate, and multiple analysis results at a low cost. With this great advantage, the new development of CBC tests and biochemistry analysis encourages further research on their clinical applications.