AN OVERVIEW OF PHARMACODYNAMIC PROPERTIES OF INHALED CORTICOSTEROIDS

Abstract

This article was aimed to review the pharmacodynamic of inhaled corticosteroids, by conducting search throughout the literature, using the PubMed and Medline, including all relevant studies that were published to beginning of 2022. The PK and PD properties of ICSs used to treat asthma, as well as the significance of their interactions, have been studied. When prescribing an ICS to an asthmatic patient, the differences in PK and PD must be considered because a better understanding of the PK/PD interrelationship of ICSs may be important to better fit with the between-patient variability and within-patient repeatability in the response to ICSs, which frequently complicate the therapeutic approach to the asthmatic patient.