Epidemiology of ovarian cancers at a tertiary cancer hospital, Hyderabad

Abstract

Ovarian cancer is the worst gynaecological cancer for women worldwide. With 1433 cases (26 per cent) overall during the study period, ovarian cancer was the second most common gynaecological malignancy at BIACH&RI. Ovarian cancer incidences marginally increased across the study period, with the highest percentage of 28.90% occurring in 2020. The largest percentage of instances occurred in the age group 51–60 years, with 31.5 per cent, followed by 41–50 years 24.3%, 61–70 years 21.5%, 31–40 years 10%, 71–80 years 6.5%, 21–30 years 4.1%, 11–20 years 1.2%, and 81–90 years 0.7%. One sex cord tumour was found at the age of one. Half of the instances included women who had gone through menopause. People between the ages of 41 and 70 account for about 77% of cases. The patient’s mean age at diagnosis of ovarian malignancy was 52.5±3.14 years. Stage III was the most common stage of ovarian cancer detection, accounting for 539 instances, followed by stage IV with 315 cases, stage I with 79 cases, and stage II with 36 cases. Stage I had a mean diagnosis age of 44.11 years, Stage II of 47.5 years, Stage III of 55 years, and Stage IV of 53 years. Nearly 49% of instances are MAHIG, with the remainder being LIGL (42%), and LIGNL (9%). Comparing patients with different gynaecological cancers, those with ovarian cancer had the highest rate of nulliparous condition (18.2 %). 941 people reported having stomach symptoms such as lumps, pain, discomfort, or distension. 25% of cases have spread to other body regions. The disease's emergence was the cause of all 31 hospital deaths (2%), which occurred. Concerning infertility, seven people are present. Ovarian cancer can run in families, as evidenced by the fact that 56 of the patients (4%) had a family history of various cancers, including malignancies of the reproductive tract.